Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury?

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Standard

Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury? / Barker, J H; Andresen, D M; Anderson, G L; Schuschke, D; Gu, J M; Gupta, S; Hjortdal, V E; Derr, J W; Banis, J C; Acland, R D.

I: Microsurgery, Bind 16, Nr. 5, 1995, s. 349-56.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Barker, JH, Andresen, DM, Anderson, GL, Schuschke, D, Gu, JM, Gupta, S, Hjortdal, VE, Derr, JW, Banis, JC & Acland, RD 1995, 'Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury?', Microsurgery, bind 16, nr. 5, s. 349-56. https://doi.org/10.1002/micr.1920160512

APA

Barker, J. H., Andresen, D. M., Anderson, G. L., Schuschke, D., Gu, J. M., Gupta, S., Hjortdal, V. E., Derr, J. W., Banis, J. C., & Acland, R. D. (1995). Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury? Microsurgery, 16(5), 349-56. https://doi.org/10.1002/micr.1920160512

Vancouver

Barker JH, Andresen DM, Anderson GL, Schuschke D, Gu JM, Gupta S o.a. Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury? Microsurgery. 1995;16(5):349-56. https://doi.org/10.1002/micr.1920160512

Author

Barker, J H ; Andresen, D M ; Anderson, G L ; Schuschke, D ; Gu, J M ; Gupta, S ; Hjortdal, V E ; Derr, J W ; Banis, J C ; Acland, R D. / Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury?. I: Microsurgery. 1995 ; Bind 16, Nr. 5. s. 349-56.

Bibtex

@article{892b48c9bf8f417384d6376c3b124be4,
title = "Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury?",
abstract = "In this study, simulated {"}poor{"} repairs applied to transverse incisions in the iliac arteries of 40 rats were the basis for comparing the effect of variations in blood flow on thromboembolism. Using vital microscopy and digital image processing, we performed 2 experiments. In the first experiment (n = 20), the reduction of post-repair blood flow by approximately 50% resulted in an 83% reduction in the total number of emboli appearing in the microcirculation of the cremaster muscle distal to the repair. In the second experiment (n = 20), the same reduction in blood flow typically resulted in larger repair-site thrombi which required significantly more time to grow to their maximum size. We conclude that reducing pedicle artery blood flow to approximately half in our rat model during reperfusion can protect the downstream microcirculation from embolic injury without increasing the incidence of thrombotic occlusion.",
keywords = "Anastomosis, Surgical, Animals, Blood Flow Velocity, Male, Microcirculation, Microsurgery, Postoperative Complications/prevention & control, Rats, Rats, Sprague-Dawley, Regional Blood Flow, Reperfusion/methods, Surgical Flaps/physiology, Thromboembolism/prevention & control",
author = "Barker, {J H} and Andresen, {D M} and Anderson, {G L} and D Schuschke and Gu, {J M} and S Gupta and Hjortdal, {V E} and Derr, {J W} and Banis, {J C} and Acland, {R D}",
year = "1995",
doi = "10.1002/micr.1920160512",
language = "English",
volume = "16",
pages = "349--56",
journal = "International Journal of Microsurgery",
issn = "0738-1085",
publisher = "JohnWiley & Sons, Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - Can varying flow velocity across an arterial anastomosis prevent thromboembolic injury?

AU - Barker, J H

AU - Andresen, D M

AU - Anderson, G L

AU - Schuschke, D

AU - Gu, J M

AU - Gupta, S

AU - Hjortdal, V E

AU - Derr, J W

AU - Banis, J C

AU - Acland, R D

PY - 1995

Y1 - 1995

N2 - In this study, simulated "poor" repairs applied to transverse incisions in the iliac arteries of 40 rats were the basis for comparing the effect of variations in blood flow on thromboembolism. Using vital microscopy and digital image processing, we performed 2 experiments. In the first experiment (n = 20), the reduction of post-repair blood flow by approximately 50% resulted in an 83% reduction in the total number of emboli appearing in the microcirculation of the cremaster muscle distal to the repair. In the second experiment (n = 20), the same reduction in blood flow typically resulted in larger repair-site thrombi which required significantly more time to grow to their maximum size. We conclude that reducing pedicle artery blood flow to approximately half in our rat model during reperfusion can protect the downstream microcirculation from embolic injury without increasing the incidence of thrombotic occlusion.

AB - In this study, simulated "poor" repairs applied to transverse incisions in the iliac arteries of 40 rats were the basis for comparing the effect of variations in blood flow on thromboembolism. Using vital microscopy and digital image processing, we performed 2 experiments. In the first experiment (n = 20), the reduction of post-repair blood flow by approximately 50% resulted in an 83% reduction in the total number of emboli appearing in the microcirculation of the cremaster muscle distal to the repair. In the second experiment (n = 20), the same reduction in blood flow typically resulted in larger repair-site thrombi which required significantly more time to grow to their maximum size. We conclude that reducing pedicle artery blood flow to approximately half in our rat model during reperfusion can protect the downstream microcirculation from embolic injury without increasing the incidence of thrombotic occlusion.

KW - Anastomosis, Surgical

KW - Animals

KW - Blood Flow Velocity

KW - Male

KW - Microcirculation

KW - Microsurgery

KW - Postoperative Complications/prevention & control

KW - Rats

KW - Rats, Sprague-Dawley

KW - Regional Blood Flow

KW - Reperfusion/methods

KW - Surgical Flaps/physiology

KW - Thromboembolism/prevention & control

U2 - 10.1002/micr.1920160512

DO - 10.1002/micr.1920160512

M3 - Journal article

C2 - 7565027

VL - 16

SP - 349

EP - 356

JO - International Journal of Microsurgery

JF - International Journal of Microsurgery

SN - 0738-1085

IS - 5

ER -

ID: 244046832