Graphical reduction of reaction networks by linear elimination of species
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Graphical reduction of reaction networks by linear elimination of species. / Saez Cornellana, Meritxell; Wiuf, Carsten; Feliu, Elisenda.
In: Journal of Mathematical Biology, Vol. 74, No. 1, 2017, p. 195–237.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Graphical reduction of reaction networks by linear elimination of species
AU - Saez Cornellana, Meritxell
AU - Wiuf, Carsten
AU - Feliu, Elisenda
PY - 2017
Y1 - 2017
N2 - We give a graphically based procedure to reduce a reaction network to a smaller reaction network with fewer species after linear elimination of a set of noninteracting species. We give a description of the reduced reaction network, its kinetics and conservations laws, and explore properties of the network and its kinetics. We conclude by comparing our approach to an older similar approach by Temkin and co-workers. Finally, we apply the procedure to biological examples such as substrate mechanisms, post-translational modification systems and networks with intermediates (transient) steps.
AB - We give a graphically based procedure to reduce a reaction network to a smaller reaction network with fewer species after linear elimination of a set of noninteracting species. We give a description of the reduced reaction network, its kinetics and conservations laws, and explore properties of the network and its kinetics. We conclude by comparing our approach to an older similar approach by Temkin and co-workers. Finally, we apply the procedure to biological examples such as substrate mechanisms, post-translational modification systems and networks with intermediates (transient) steps.
KW - math.DS
KW - q-bio.MN
KW - 92C42, 80A30
U2 - 10.1007/s00285-016-1028-y
DO - 10.1007/s00285-016-1028-y
M3 - Journal article
C2 - 27221101
VL - 74
SP - 195
EP - 237
JO - Journal of Mathematical Biology
JF - Journal of Mathematical Biology
SN - 0303-6812
IS - 1
ER -
ID: 160402366