Conflicting results in SNP genotype assessment

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Standard

Conflicting results in SNP genotype assessment. / Hansen, Lise Lotte; Madsen, Bo Eskerod; Pedersen, Kristina; Wiuf, Carsten.

I: BioTechniques, Bind 43, Nr. 6, 01.12.2007, s. 756-762.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hansen, LL, Madsen, BE, Pedersen, K & Wiuf, C 2007, 'Conflicting results in SNP genotype assessment', BioTechniques, bind 43, nr. 6, s. 756-762. https://doi.org/10.2144/000112675

APA

Hansen, L. L., Madsen, B. E., Pedersen, K., & Wiuf, C. (2007). Conflicting results in SNP genotype assessment. BioTechniques, 43(6), 756-762. https://doi.org/10.2144/000112675

Vancouver

Hansen LL, Madsen BE, Pedersen K, Wiuf C. Conflicting results in SNP genotype assessment. BioTechniques. 2007 dec. 1;43(6):756-762. https://doi.org/10.2144/000112675

Author

Hansen, Lise Lotte ; Madsen, Bo Eskerod ; Pedersen, Kristina ; Wiuf, Carsten. / Conflicting results in SNP genotype assessment. I: BioTechniques. 2007 ; Bind 43, Nr. 6. s. 756-762.

Bibtex

@article{763bbad9a58f45e3b1acd32dc791b58d,
title = "Conflicting results in SNP genotype assessment",
abstract = "Single nucleotide polymorphisms (SNPs) are highly abundant in the genome and especially useful in the search for disease susceptibility genes via population-based association or linkage studies. Therefore, there is a strong need for high throughput and reliable methodologies to assess the SNP genotypes. Despite an unambiguous result of an SNP analysis, with the use of a commercial kit based on primer extension, subsequent sequencing analysis revealed that a proportion of the genotypes was not correctly assessed. The problem we have encountered may originate from specific structures in the genomic DNA sequence, rather than being a methodological problem.",
author = "Hansen, {Lise Lotte} and Madsen, {Bo Eskerod} and Kristina Pedersen and Carsten Wiuf",
year = "2007",
month = dec,
day = "1",
doi = "10.2144/000112675",
language = "English",
volume = "43",
pages = "756--762",
journal = "BioTechniques",
issn = "0736-6205",
publisher = "Informa Healthcare",
number = "6",

}

RIS

TY - JOUR

T1 - Conflicting results in SNP genotype assessment

AU - Hansen, Lise Lotte

AU - Madsen, Bo Eskerod

AU - Pedersen, Kristina

AU - Wiuf, Carsten

PY - 2007/12/1

Y1 - 2007/12/1

N2 - Single nucleotide polymorphisms (SNPs) are highly abundant in the genome and especially useful in the search for disease susceptibility genes via population-based association or linkage studies. Therefore, there is a strong need for high throughput and reliable methodologies to assess the SNP genotypes. Despite an unambiguous result of an SNP analysis, with the use of a commercial kit based on primer extension, subsequent sequencing analysis revealed that a proportion of the genotypes was not correctly assessed. The problem we have encountered may originate from specific structures in the genomic DNA sequence, rather than being a methodological problem.

AB - Single nucleotide polymorphisms (SNPs) are highly abundant in the genome and especially useful in the search for disease susceptibility genes via population-based association or linkage studies. Therefore, there is a strong need for high throughput and reliable methodologies to assess the SNP genotypes. Despite an unambiguous result of an SNP analysis, with the use of a commercial kit based on primer extension, subsequent sequencing analysis revealed that a proportion of the genotypes was not correctly assessed. The problem we have encountered may originate from specific structures in the genomic DNA sequence, rather than being a methodological problem.

UR - http://www.scopus.com/inward/record.url?scp=37349077842&partnerID=8YFLogxK

U2 - 10.2144/000112675

DO - 10.2144/000112675

M3 - Journal article

C2 - 18251251

AN - SCOPUS:37349077842

VL - 43

SP - 756

EP - 762

JO - BioTechniques

JF - BioTechniques

SN - 0736-6205

IS - 6

ER -

ID: 203900563