Seminar in applied mathematics and statistics
SPEAKER: Todd Ogden (Columbia University).
TITLE: Towards precision medicine: Determining optimal treatments based on complex data.
ABSTRACT: A major goal in precision medicine is to make optimal patient-specific treatment decisions using data observed at baseline. For the treatment of neuropsychiatric disorders, available data may include clinical variables and measures of behavioral/cognitive performance, as well as complex imaging data. In the context of a large multi-site randomized trial to study depression (the EMBARC study) , I will discuss some methods for treatment selection using imaging and other baseline data. Making the most efficient use of complex data will require dimension reduction, penalization, and other techniques common in functional data analysis. This will allow us to properly take into account the structure of the data. I will describe some new methodological advances and illustrate them with preliminary results using the EMBARC data set.
Tea and chocolate will be served in room 04.4.19 after the seminar.
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Upcoming events:
Friday, February 8, 2019 at 14.15: Massimiliano Tamborrino
Friday, February 15, 2019 at 14.15: Irene Tubikanec