Recombination in human mitochondrial DNA?

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Recombination in human mitochondrial DNA? / Wiuf, Carsten.

In: Genetics, Vol. 159, No. 2, 17.11.2001, p. 749-756.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Wiuf, C 2001, 'Recombination in human mitochondrial DNA?', Genetics, vol. 159, no. 2, pp. 749-756.

APA

Wiuf, C. (2001). Recombination in human mitochondrial DNA? Genetics, 159(2), 749-756.

Vancouver

Wiuf C. Recombination in human mitochondrial DNA? Genetics. 2001 Nov 17;159(2):749-756.

Author

Wiuf, Carsten. / Recombination in human mitochondrial DNA?. In: Genetics. 2001 ; Vol. 159, No. 2. pp. 749-756.

Bibtex

@article{cf2e2a9aeab24870ad98e46433018bd2,
title = "Recombination in human mitochondrial DNA?",
abstract = "The possibility of recombination in human mitochondrial DNA (mtDNA) has been hotly debated over the last few years. In this study, a general model of recombination in circular molecules is developed and applied to a recently published African sample (n = 21) of complete mtDNA sequences. It is shown that the power of correlation measures to detect recombination in circular molecules can be vanishingly small and that the data are consistent with the given model and no recombination only if the overall heterogeneity in mutation rate is <0.09.",
author = "Carsten Wiuf",
year = "2001",
month = nov,
day = "17",
language = "English",
volume = "159",
pages = "749--756",
journal = "Genetics",
issn = "1943-2631",
publisher = "The Genetics Society of America (GSA)",
number = "2",

}

RIS

TY - JOUR

T1 - Recombination in human mitochondrial DNA?

AU - Wiuf, Carsten

PY - 2001/11/17

Y1 - 2001/11/17

N2 - The possibility of recombination in human mitochondrial DNA (mtDNA) has been hotly debated over the last few years. In this study, a general model of recombination in circular molecules is developed and applied to a recently published African sample (n = 21) of complete mtDNA sequences. It is shown that the power of correlation measures to detect recombination in circular molecules can be vanishingly small and that the data are consistent with the given model and no recombination only if the overall heterogeneity in mutation rate is <0.09.

AB - The possibility of recombination in human mitochondrial DNA (mtDNA) has been hotly debated over the last few years. In this study, a general model of recombination in circular molecules is developed and applied to a recently published African sample (n = 21) of complete mtDNA sequences. It is shown that the power of correlation measures to detect recombination in circular molecules can be vanishingly small and that the data are consistent with the given model and no recombination only if the overall heterogeneity in mutation rate is <0.09.

UR - http://www.scopus.com/inward/record.url?scp=0034754464&partnerID=8YFLogxK

M3 - Journal article

C2 - 11606549

AN - SCOPUS:0034754464

VL - 159

SP - 749

EP - 756

JO - Genetics

JF - Genetics

SN - 1943-2631

IS - 2

ER -

ID: 203901938