Parameter estimation in neuronal stochastic differential equation models from intracellular recordings of membrane potentials in single neurons: a Review

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Dokumenter

Dynamics of the membrane potential in a single neuron can be studied by estimating biophysical parameters from intracellular recordings. Diffusion processes, given as continuous solutions to stochastic differential equations, are widely applied as models for the neuronal membrane potential evolution. One-dimensional models are the stochastic integrate-and-fire neuronal diffusion models. Biophysical neuronal models take into account the dynamics of ion channels or synaptic activity, leading to multidimensional diffusion models. Since only the membrane potential can be measured, this complicates the statistical inference and parameter estimation from these partially observed detailed models. This paper reviews parameter estimation techniques from intracellular recordings in these diffusion models.
OriginalsprogEngelsk
TidsskriftJournal de la Société Française de Statistique
Vol/bind157
Udgave nummer1
StatusUdgivet - 2016

Antal downloads er baseret på statistik fra Google Scholar og www.ku.dk


Ingen data tilgængelig

ID: 160453255